- S2 Games
- Saffire
- SCi Games
- Screenplay
- SCR Adventures
- Sega
- Sennari Interactive
- Shine Studio
- Sierra
- Sigil Games Online
- Silicon Knights
- Silmarils
- Silversoft
- Simon & Schuster Interactive
- Simutronics
- Sirius Software
- Sirtech
- SNK
- Snowblind Studios
- Softdisk
- Software of Sweden
- Software Projects Ltd
- Songbird Productions
- Sonic Team
- Sony
- SouthPeak Interactive
- Spectrum Adventure Exchange Club
- Spellbound Studios
- Spiderweb Software
- Spinnaker
- Sports Interactive
- Square Enix
- SSI
- Stainless Steel Studios
- Stardock
- Stormfront Studios
- Strategy First
- St Brides School
- Summit Software
- Superior Software
- SW Games
- Synapse Software
Also see:
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