Also see:
- ..Sacred(1)
- ..Saga of Heroes(5)
- ..Saga of Ryzom, The(4)
- ..SaGa Series(1)
- ..Saints of Virtue(1)
- ..Saints Row Series(1)
- ..Samurai Shodown Series(1)
- ..Sam and Max Hit the Road(1)
- ..Sands of Time, The(1)
- ..San Andreas - Grand Theft Auto(1)
- ..San Francisco Rush Extreme Racing(1)
- ..Savage Eden - The Battle for Laghaim(1)
- ..Scorched Earth(1)
- ..Scrabble(2)
- ..Seaman(1)
- ..Second Life(93)
- ..Sega Rally 2(1)
- ..Seiken Densetsu Series(2)
- ..Sensible Soccer Series(3)
- ..Septerra Core(1)
- ..Serpent Isle(2)
- ..Settlers Series, The(2)
- ..Seven Kingdoms Series(1)
- ..Shadowbane(4)
- ..ShadowFlare(1)
- ..Shadows of Angmar(39)
- ..Shadow Hearts Series(4)
- ..Shaiya(2)
- ..Shattered Galaxy(1)
- ..Shenmue Series(1)
- ..Shining Force Series(2)
- ..Shogo Mobile Armor Division(1)
- ..Shogun - Total War(1)
- ..Sid Meier's Civilization Series(18)
- ..Sid Meier's Colonization(3)
- ..Sid Meier's SimGolf(2)
- ..Siege of Avalon(1)
- ..Silent Hill Series(6)
- ..Silent Hunter Series(1)
- ..Silkroad Online(2)
- ..Silver Star Story(1)
- ..SimCity Series(10)
- ..Simpsons Road Rage, The(1)
- ..Sim Games(130)
- ..Sith Lords, The(1)
- ..Skies of Arcadia Series(1)
- ..Slingo(1)
- ..Smart Games Series(1)
- ..Snake Games(4)
- ..Snood(1)
- ..SOCOM - U.S. Navy SEALs Series(2)
- ..Soda Offroad Racing(1)
- ..Soldat(4)
- ..Soldier of Fortune(5)
- ..Solitaire(29)
- ..Sonic the Hedgehog Games(12)
- ..Soul Calibur Series(2)
- ..Sovereign(1)
- ..Space Federation - Browser Based(1)
- ..Space Invaders(4)
- ..Space Quest Series(2)
- ..Space Racer(1)
- ..Spades(2)
- ..SpellForce - The Order of Dawn(2)
- ..Splinter Cell(2)
- ..Splinter Cell Series(3)
- ..Spore(2)
- ..Spyro Series(1)
- ..Stacked(1)
- ..StarCraft - Ghost(1)
- ..StarCraft Series(53)
- ..Starfleet Command Series(4)
- ..Stargate Worlds(1)
- ..Starlancer(1)
- ..Stars(2)
- ..Starship Titanic(2)
- ..Starsiege Series(1)
- ..Starwing(2)
- ..Star Control Series(3)
- ..Star Fox Series(4)
- ..Star Trek Games(24)
- ..Star Trek Online(37)
- ..Star Wars Games(102)
- ..State of Emergency(1)
- ..Steel Beasts(2)
- ..Steel Panthers - World at War(1)
- ..Stormreach(9)
- ..Streets of LA(1)
- ..Street Fighter Series(10)
- ..Strider Series(1)
- ..Stronghold(2)
- ..Stupid Invaders(1)
- ..Stygian Abyss, The(1)
- ..Subspace(3)
- ..Sudoku(14)
- ..Suffering, The(1)
- ..Suikoden Series(1)
- ..Summer Sports - Paradise Island(1)
- ..Super Columbine Massacre RPG(1)
- ..Super Mario Games(25)
- ..Super Metroid(1)
- ..Super Smash Bros. Series(7)
- ..Supremacy(1)
- ..Supreme Commander(2)
- ..Syberia Series(1)
- ..Syphon Filter Series(1)
- ..System Shock Series(3)