- Cameron, Mike
- Caminiti, Ken
- Campanella, Roy
- Canseco, Jose
- Carlton, Steve
- Carter, Gary
- Castilla, Vinny
- Cepeda, Orlando
- Chavez, Eric
- Christenson, Ryan
- Cirillo, Jeff
- Clark, Tony
- Clayton, Royce
- Clemens, Roger
- Clemente, Roberto
- Cobb, Ty
- Collins, Eddie
- Cone, David
- Conigliaro, Tony
- Conine, Jeff
- Contreras, Jose
- Coomer, Ron